| Author(s) |
A. M. Al-Mayouf and Adil M. Al-Sulaim |
| Affiliation |
Department of Chemistry, College of Science King Saud University, PO.Box 2455, Riyadh-1451, Saudi Arabia |
| Title |
A Novel Method for the Determination ofIsoprenaline in a Pharmaceutical Preparation by Differential-pulse Voltammetry |
| Source |
Journal of King Saud University. Science. Volume 11, No 1. (1999/1419) |
| Abstract |
A differential-pulse voltammetric procedure is described for the determination of Iow concentrations of isoprenaline in pure form in a pharmaceutical preparation. At pH 0.5 and with 0.1 M potassium nitrate as the base electrolyte, the electrode response was linearly proportional to the concentration of isoprenaline in the range 10-'-10-2 M. The detection limit was 1x 10.6 M and the relative standard deviation (n=10) was 1.2% at 4xlO-4 M isoprenaline. The degree of interference from some excipients, added to the pharmaceutical product, on the differential pulse voltammetric signal for isoprenaline was evaluated. No matrix separation is required. |
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