King Saud UniversityKSU Libraries Libraries Catalog

Author(s) A. M. Al-Mayouf and Adil M. Al-Sulaim
Affiliation Department of Chemistry, College of Science King Saud University, PO.Box 2455, Riyadh-1451, Saudi Arabia
Title A Novel Method for the Determination ofIsoprenaline in a Pharmaceutical Preparation by Differential-pulse Voltammetry
Source Journal of King Saud University. Science. Volume 11, No 1. (1999/1419)
Abstract A differential-pulse voltammetric procedure is described for the determination of Iow concentrations of isoprenaline in pure form in a pharmaceutical preparation. At pH 0.5 and with 0.1 M potassium nitrate as the base electrolyte, the electrode response was linearly proportional to the concentration of isoprenaline in the range 10-'-10-2 M. The detection limit was 1x 10.6 M and the relative standard deviation (n=10) was 1.2% at 4xlO-4 M isoprenaline. The degree of interference from some excipients, added to the pharmaceutical product, on the differential pulse voltammetric signal for isoprenaline was evaluated. No matrix separation is required.