The main objective of this book is to demonstrate how to use the bases immunological and molecular knowledge slum for the production of new vaccines and improving existing vaccines, has been first described the mechanisms of pathogenicity of infectious and parasitic organisms and the subsequent responses innate and adaptive immunity, which had disturbed, and then reviewed the methods used to identify the components of the vaccine antigens , the concomitant application of new techniques of expression and delivery tankers containing living resuming association, which consists of 11 chapters.